It suppresses the wakefulness system
However, these two patient populations may inherently have pre-existing emotional issues
Currently, the concept of the Microbiota- Gut-Brain axis (MGB) encompasses the interaction of the hostmicrobiota and its communication with the CNS, endocrine chemical signaling, immune regulation, microbiota and metabolic effects, and barrier functions in the brain and gut [49,50]
10.1073/pnas.1609905114 Proc
The combined benefits of reduced appetite, increased satiety, slower gastric emptying, and improved blood sugar control make GLP-1 therapy an effective weight loss solution, particularly for individuals who have found it challenging to lose weight with diet and exercise alone
Why this matters for semaglutide