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Using the CMap database, we found that cinchonine presented the highest score indicating that this compound exerts GLP-1R agonist-like effects

The pronounced spatial heterogeneity of the solid TME can lead to variable activation efficiencies across different lesion regions, potentially compromising therapeutic thoroughness (Table 2) [174, 175]

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Mol Pain 14:1744806918795930 Gong Q, Lin Y, Lu Z, Xiao Z (2020) Microglia-Astrocyte Cross Talk through IL-18/IL-18R Signaling Modulates Migraine-like Behavior in Experimental Models of Migraine

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Plaintiffs claim the companies aggressively marketed these drugs while failing to warn about life-altering side effects