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Researchers also examined major adverse CV events in patient subgroups on the basis of major adverse CV event rates in the placebo group, the presence or absence of CVD, HbA1c level, trial duration, treatment dosing interval, structural homology to human GLP-1 or exendin-4, BMI, age and eGFR

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Concerns that require attention: carpal tunnel-style tingling (signals excessive GH/IGF-1), elevated fasting glucose, persistent joint pain, and rare immunogenicity reactions

It co-localizes with multiple hormones and neurotransmitters, suggesting broad regulatory functions

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These conditions probably contributed to the significant concentration of GSSG in the shrimp and turbot tissues