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Women with insulin resistance or central adiposity derive larger metabolic advances from incretin-mimetic peptides and larger reproductive reward when weight loss occurs

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the specific preparation route is as follows: wherein, the substituent R in the compound 1, the compound 2 and the compound 4 is alkane, alkene, alkyne or aromatic hydrocarbon

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BMI body mass index DPP dipeptidyl peptidase DPL DPP4-like protein FAP fibroblast activation protein GIP glucose-dependent insulinotropic polypeptide GLP-1 glucagon-like peptide-1 QPP quiescent cell proline dipeptidase SDF-1 Stromal cell-derived factor-1 T2DM type 2 diabetes mellitus

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