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A compelling body of circumstantial evidence suggests that IGF/IGF-1R and insulin/insulin receptor (IR) serve overlapping functions in selected tissues including the skeleton

Research endpoints: cellular NAD+ quantification

Remember that GLP-1 receptor agonists should not be combined with DPP-4 inhibitors, as both work on the incretin system

For SA--gal staining of frozen tissue sections ( n = 10 per group), pancreas sections were thawed, fixed and stained using a senescence -galactosidase staining kit (Cell Signaling, cat

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