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The signal was greatest for the executive-function cognitive domain, but study limitations precluded definitive conclusions

Sterility concerns represent another consideration, particularly for Ozempic pens used beyond the 56-day in-use period

The drug remains in Phase 3 clinical trials (see ClinicalTrials

The progressive ramp through the cycle is intentional: it allows the body to respond to the compound gradually, lets the provider assess tolerance and response before increasing the dose, and avoids the unnecessary load of starting at maximum dosing when the tissue is still in early repair phases

Nature 2015;526:6605

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