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Furthermore, total insulin use was reduced significantly in the 7-mg and 14-mg oral semaglutide groups when compared with placebo, suggesting an insulin-sparing effect with treatment

This brings the advantages of personalized GLP-1 prescription and everyday healthcare treatments firmly to the mainstream, rather than a benefit only available to a privileged few

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Thus, severe sodium restriction in animals with early heart disease could theoretically be detrimental by early and excessive activation of the RAA system (Pedersen 1996