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Hormonal shifts, reduced muscle mass, and slower metabolic responses can cause the body to store weight more easily

At that point, metabolic adaptation is just beginning, lifestyle habits are still forming, and the biological drivers of regain are at their strongest

The expression levels of ABCA1 and ATP-binding cassette G1 (ABCG1) can also be increased by GLP-1, which inhibits the transformation process of macrophages into foam cells and reduces the level of intracellular cholesterol

[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Steinberg W.M., Rosenstock J., Wadden T.A., Donsmark M., Jensen C.B., DeVries J.H