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An example of altered chromatin accessibility and gene expression is shown for TGFBR2 in Fig

These conditions can increase the risk of serious thyroid problems

Collectively, these findings underscore that lactylation orchestrates PH progression through a multi-layered network, coupling metabolic stress to epigenetic remodeling and protein functional changes

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Apart from the insulinogenic effect caused by an increase in blood glucose, feeding also activates different signaling networks in the central nervous system, as well as incretin production by the gut and signaling by nutrient receptors [1]