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Prominent among its multiple effects is the inhibition of nuclear factor kappa-B (NF-kB) signaling

In fact, it has been shown that the translation of senescence chondrocytes in mice knee joint resulted in OA phenotype, characterized by leg pain, impaired mobility, and radiographic and histological changes (Xu et al., 2017)

Directions For Use: Apply on wet skin, gently massage in circular motions (face: 3060 sec, body: 12 min), then rinse thoroughly

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