Efficacy and safety Beyond its primary use for type 2 diabetes, tirzepatide has been explored for its potential in treating obesity, osteoarthritis of the knee, atherosclerosis, and other metabolic diseases
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2021;106(5):e2055-e2068
However, at 50 mg, oral semaglutide (OASIS 1) narrowed that gap substantially, achieving 15.1 percent weight loss at 68 weeks, approaching injectable performance

Used when: Oral intake is inadequate The gut is functional ASPEN Golden Rule: If the gut works, use it or loose it . Core Components of EN Formulas All EN formulas contain: Protein (intact, peptides, or amino acids) Carbohydrates Fat Water Electrolytes Vitamins & Trace Elements What really differentiates formulas: Protein form Fat composition Osmolality Fiber content Disease-specific modifications Classification of EN Formulas (ASPEN-Based) Intact protein Require normal digestion & absorption Used in: Normal GI function Most hospitalized patients Examples: Ensure | Jevity | Osmolite - (-) Protein as peptides Often enriched with MCTs Easier absorption Used in: Mildmoderate malabsorption Pancreatitis Partial short bowel syndrome Feeding intolerance Examples: Peptamen | Vital | Monogen Free amino acids Minimal fat High osmolality Used in: Severe malabsorption Severe short bowel syndrome Refractory intolerance Example: Vivonex To view or add a comment, sign in One major nutraceutical trend: Targeted nutrition

The downside about this method is that we employ many other combinations that may increase the complexity of the treatment (not for us, but for patients to understand & follow), acknowledging that if you can take tablets, it is a relatively straightforward adjunct