The real advantage comes from personalization rather than adding supplements generically
They work by mimicking or enhancing the natural signals that trigger GH release, rather than providing exogenous hormone
B., Hernandez-Lagunas, L., Ranguelova, K., Dikalov, S
(2020) added preformed fibrils (PFF) of -Syn exogenously to the cultured neurons and found that at day 14 inclusions composed of loose fibrils start to interact with organelles, and at day 21 high enrichment of proteins from the mitochondria (including complexes I, II, and V), the endoplasmic reticulum, and the Golgi were detected in the Lewy body-like inclusions, corresponding to the reduction of the maximum OXPHOS capacity and maximum electron transport capacity at day 21
When taken in the correct dosage and using certified products, they are generally beneficial and safe
Triple agonism enhances metabolic benefits beyond just adipose tissue reduction