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Severe deficiency can lead to irreversible brain and nerve damage

In the retrospective study of Lautenbach et al., a mean weight loss of 10.3% with 85% of patients achieving a weight loss of 5% after 6 months GLP1-RA therapy was reported with semaglutide, 0.5 mg, weekly subcutaneous injection

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Recent investigations (20232025) have moved beyond simple association to elucidating precise molecular mechanisms, particularly involving the gut-pancreas axis, incretin hormone regulation, and the mitigation of systemic oxidative stress (434)