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The most important caveat is that biotin can interfere with thyroid blood tests, causing falsely abnormal results

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If you are starting tirzepatide for the first time and your pharmacy sends a 40 mg/mL vial, ask them to reconsider

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In placebo-controlled adjunctive epilepsy trials in adults receiving topiramate 200 to 1,000 mg/day, hot flashes (1% to 2%), drug-induced body odor (0% to 1%), skin disorder (1% to 2%), hyperhidrosis (1% or less), and erythematous rash (1% or less) were reported with equal or greater frequency than placebo