Historically, the obesity pharmacotherapy literature notes early trial signals and also that development was terminated after failure to show meaningful weight loss in a larger, longer trial (as summarized in a peer-reviewed review discussing a 12-week signal and a later 24-week negative result)
Some HIV drugs may cause this side effect (increased fat in the upper back and stomach areas, decreased fat in the arms and legs) (Fun fact: In 2019, the FDA approved an enhanced version of EGRIFTA that requires a five-fold lower injection volume and remains stable at room temperature) Believe it or not, lipodystrophy was one of the unwanted side effects that had arisen from the first line of HIV treatments developed in the 1990s: Since it first became available in the mid-1990s, highly active antiretroviral therapy (HAART) has saved lives and improved health and quality of life for countless people living with HIV but the drugs are not without their downsides
Causes & Solutions Why am I still feeling hungry on Mounjaro
Have you had any trauma or swallowed a foreign object accidentally
The dosing schedule looks complicated
The effect of exenatide once weekly on carotid atherosclerosis in individuals with T2D: An 18-month randomized placebo-controlled study