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Mutations in these regions alter the GDH antenna-like domain and weaken the binding capacity of GTP binding domains with GTP, thereby compromising the inhibitory effect of GTP on GDH activity
Each monofilament was tested five times
Neither alone can reduce the signal as much as both together
This improvement is typically linked to better blood glucose control, weight loss, and overall metabolic health rather than a direct pharmacological effect on energy
doi: 10.1016/j.semcdb.2014.02.012 62 ChandraAKChakrabortyA
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