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A significance level of alpha = 0.05 was adopted for all analyses

Wound Healing & Microcirculation: Researching how localized VEGF production accelerates the repair of damaged dermal layers and improves blood flow

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Because pyridostigmine is a highly ionized quaternary ammonium compound, under normal conditions it does not readily cross the blood-brain barrier (BBB) (Dunn et al, 1997

An ongoing phase IIb RCT, currently recruiting patients, aims to evaluate the safety and efficacy of this drug in NASH with a primary outcome consisting in NASH resolution without worsening of fibrosis

Further clinical evaluation (e.g., rheumatology referral) may be appropriate for VYVANSE-treated patients who develop signs or symptoms of peripheral vasculopathy