Data extraction Information on the baseline characteristics of the samples enrolled included age, gender, proportion of patients with T2D, baseline BMI, TBWL%, waist circumference, body composition, proportion of patients achieving at least 5%, 10%, 15%, 20%, and 25% body weight reduction, remission or improvement/resolution of obesity-related complications, SAE, mortality, MACE, FPG, HbA1c, lipid profile, estimated glomerular filtration rate (eGFR), creatinine, albuminuria, mental health parameters and QoL
CLML 13(S2):S376-77, 2013
No setup fee, just a small per-vial cost, printed and applied in-house
For type 2 diabetes management , NICE guidance (NG28) recommends GLP-1 agonists as second- or third-line therapy when metformin and other oral agents provide inadequate glycaemic control, or as an alternative to insulin in appropriate patients
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therefore, research into longer acting GCGR/GLP-1R dual agonists is warranted