Ghrelin, secreted from gastric and duodenal enteroendocrine cells, is one of the only GI tractsecreted peptides to decrease postprandially and to increase feeding when administered exogenously (18)
The honest answer to the question is indirect: semaglutide has been shown to reduce congestion-related symptoms in one specific population studied in a randomized trial, and weight reduction can plausibly ease some forms of dependent lower-limb swelling, but neither of those makes it a treatment for edema
Zhou, W
It is especially beneficial for individuals aiming for weight management, those at significant cardiovascular risk, or patients seeking simplified treatment regimens
The intestinal lining becomes hypersensitive, and the underlying musculature is already compromised, making it harder for your body to tolerate rapid changes in gastric motility or medication side effects
Activated platelets release a variety of mediators that enhance activation, adhesiveness, and attraction of more platelets, as well as vasoconstriction