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GLP-1 expression was downregulated in wild-type Lox5 cells knocked out by FNDC5, and the induced expression of lipolysis and autophagy-related genes and proteins were also inhibited, such as adipose triacylglyceride lipase (ATGL), hormone-sensitive lipase (HSL), and hepatic lipase deficiency gene (LIPC)

Nov 2006;36(6):1345-59, viii

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In modern peptide research, BAC water is preferred over plain sterile water because of two practical realities: lyophilised peptide vials are typically over-filled (giving 3060 days of working stock), and laboratories need a diluent that tolerates repeated stopper puncture without microbial bloom