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To further support this finding, immunohistochemical staining for IDO expression revealed a correlation between high IDO expression and low levels of immune cells CD3 + , CD8 + , and CD57 + [129]

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In this project, ASP functions as the hydrophilic segment, whereas lipophilic BBR constitutes the hydrophobic segment, encapsulating HNK through redox-sensitive disulfide bonds (ASP-BBR-PM@HNK)

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