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Hypothalamic PPAR has been shown to play a role in the regulation of appetite, presumably via enhanced expression of MCD, with the use of pirinixic acid which is a PPAR agonist

TABLE 1 Immunomodulatory effects and mechanisms of the extracts of Zingiber and Alpinia species

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Lancet Diabetes Endocrinol (2015) 3(11):86675

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