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Taken together, these results indicate that B2M-CuS NPs can efficiently eliminate senescent cells through the conversion of H 2 O 2 into toxic ROS that induce apoptosis

Animal studies show no toxicity at therapeutic doses, but human data is insufficient for regulatory approval

Figure 3 Figure 4 Figure 5 The K m and V max We calculated the K m and V max parameters from Lineweaver-Burk plots, and Table 3 mentions the values

J Leukoc Biol 102(2):343349 Fridlender ZG et al (2009) Polarization of tumor-associated neutrophil phenotype by TGF-beta: N1 versus N2 TAN