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PET-negative (across the entire cohort, within the CI/CN subgroups, and specifically between CN PET-negative and CI PET-positive individuals)

Interestingly, GSTO1 was identified as one of the potential cellular targets of piperlongumine, an electrophilic compound exerting selective cytotoxicity against cancer cells through an oxidative cell death mechanism (Supplementary Table 25) 37

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BMC Complementary and Alternative Medicine, 14 , 511