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*Correspondence: Xiaohan Zhai, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Major depression is treated by various pharmacological and non-pharmacological interventions

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47,48 There are two populations affected by HAPE: unacclimated lowlanders and acclimatized residents returning from low altitudes (re-entry)

Deficiency of eNOS can result in endothelial dysfunction leading to diabetic nephropathy