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Studies show that ROS play an important role in the pathogenesis of kidney damage caused by contrast agents and that it might be possible to reduce this damage by antioxidants such as MESNA [22]

Singh S, Wright EE Jr, Kwan AY, Thompson JC, Syed IA, Korol EE, et al

For a deeper dive, you can read more info about what NAD is from a doctors perspective

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And understanding this chemistry helps you evaluate products and recognize when something isn't working as intended