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Adverse events typically decrease as your body adjusts to the medication within the first 812 weeks

The comparison with Retatrutide is particularly relevant because both come from Eli Lilly and share the GIP/GLP-1 dual agonist foundation

Its often linked to being overweight, living with obesity, or having type 2 diabetes

This phase tests patience, as weekly changes become less dramatic even though cumulative results continue building

Compare Side Effect Profiles Similar GI Side Effects Different Side Effect Profiles Orlistat GI effects from fat malabsorption Phentermine Stimulant side effects Jardiance UTI risks View all 48 compound safety comparisons

Symptoms typically appear around weeks 4 to 6, peak between weeks 6 and 8, and resolve substantially by week 12