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This result was unexpected, but could be explained by the finding that in the absence of HSL, adipocytes undergo a compensatory decrease in the re-esterification of FA that results in decreased resynthesis of TAG and increased liberation of FA to the vasculature (144)
All comparisons were statistically significant. 7 19.7% of tirzepatide users lost 30% of their body weight, a dramatic outcome for pharmacologic obesity treatment
Hazard ratios for time to first confirmed MACE were all below 1.0 in subjects treated with semaglutide vs placebo, irrespective of baseline CV risk profile (Fig
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