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Jger R et al

Key finding: AOD-9604 failed to produce statistically significant weight loss compared to placebo in a clinical trial

The immune cells are being continuously flooded by toxic Reactive Oxygen Species (ROS) and are frantically up-regulating glutathione production to survive the onslaught

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Among the known regulatory processes, reversible post-translational modifications (PTMs) are regarded as critical regulators that control cellular quiescence and proliferation (Chen et al., 2020)