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Ozempic is approved for this indication in the USA, EU, Canada, Japan, and Australia 2,3,4,5,6

doi: 10.1111/head.13081 [DOI] [PubMed] [Google Scholar] 161.Karsan N, Goadsby PJ

Compared to dual GIP/GLP-1 agonists such as ZepBound, Wegovy may produce slightly slower or less dramatic results in some patients, but it remains one of the most reliable and broadly effective agents available

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However, in patients with IEMs, carnitine-TMAO conversion is not established, and it has been postulated that dietary protein restriction may mitigate gut microbial breakdown of supplemental l-carnitine, similar to what is seen in vegan/vegetarian individuals