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Plateau effect after a certain point, improvement slows or stabilizes, and further gains require more intensive or adjunctive strategies

cycle-based Human evidence level Moderate Clinical trials

These results suggest that GCLC may serve as a promising biomarker for early diagnosis and a potential therapeutic target in PD

However, the broad spectrum of symptoms belonging to either musculoskeletal or cardiorespiratory symptom clusters was similar in both wild-type and VOC infections, though more studies with higher number of observations/patients are needed to confirm the effects (183)

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