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Start Understand the mechanism Use the quick facts, pathway overview, and research notes to understand why the compound is discussed
Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)
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Gesek and Schoolwerth, 1991
However, the main muscle anabolic effects of GH are believed to be indirectvia inducing the hepatic generation of IGF-1 triggering the IGF-1-Akt-mTOR pathway
Bearing that in mind, we can see this as a rather weak antioxidant
LiNWenLWangFWangTLiTQiaoMet alMechanism of mitigating effect of wheat germ peptides on lead-induced oxidative damage in PC12 cells
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