As humans age, their natural levels of GHK decline, going from around 200ng/mL in the plasma of a 20-year-old to 80ng/mL in a 60-year-old
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In 2011, for example, researchers who administered 1,000mg per day of non-liposomal glutathione found "no significant changes were observed in biomarkers of oxidative stress" in participants after four weeks.2 In contrast, a 2019 study of identical length administered liposomal glutathione at 500-1,000mg doses and saw significant decreases in oxidative stress biomarkers plus improvements in immune system markers.3 Two of our top recommended glutathione supplements are liposomal, by the way: Codeage Liposomal Glutathione, our recommendation for most people Quicksilver Scientific Glutathione, our top liquid glutathione supplement Branded glutathione Glutathione supplements often use one of two branded versions of glutathione that are formulated to improve absorption: Setria or Opitac
Oral GHK-Cu is more convenient but faces significant absorption challenges due to enzymatic degradation in the digestive tract
Promotion of Wound Healing Early clinical trials showed that GHK-Cu could accelerate the healing of surgical wounds and severe burns by promoting the migration of repair cells to the injured area
Similarly, the excretion of glutathione into breast milk and its effects on the nursing infant are not well understood
