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I started with small changes

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Dennis-Wall JC, Culpepper T, Nieves C Jr, Rowe CC, Burns AM, Rusch CT, Federico A, Ukhanova M, Waugh S, Mai V, Christman MC, Langkamp-Henken B

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This trial demonstrated that Retatrutide simultaneously addressed multiple health complications: participants experienced dramatic reductions in knee osteoarthritis pain (75.8% improvement), significant drops in blood pressure (14 mmHg systolic), and improvements in cardiovascular risk markers