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Particularly, manganese dioxide (MnO 2 ) nanosheets are usually selected as GSH biosensors, owing to their excellent colloidal stability, absorption capability, redox chemistry and biocompatibility 22,23,24

doi: 10.1021/bi0618565

The enzyme was dissolved in phosphate-buffered saline at pH 7.4, sterilized through a 0.22-m membrane, and administered under ultrasound guidance

Some patients achieve adequate appetite control at lower maintenance doses (5-10 mg), while others require maximum dosing

Changes in the gut microbiome during HS can also lead to reduced production of anti-inflammatory SCFAs, which in turn inhibit pattern recognition receptors (PRRs) involved in pathogen recognition and reduce the production of IL-10 and TGF- (218)