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Glutathione is involved in multiple cellular defense systems throughout the body

Such impairments closely parallel the mitochondrial respiratory deficits and elevated oxidative markers reported in cortical and limbic regions of depressed individuals, which would impair energy-dependent neuroplastic processes, intracellular signal transduction cascades, and activity-dependent protein synthesis required for synaptic maintenance, dendritic remodelling, and adaptive circuit function [138, 143]

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