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Cancer cells face a range of intrinsic and extrinsic adverse/stressful conditions, such as nutrient and oxygen deficiency, and have consequently developed means to adapt their metabolism in order to survive

She then received neoadjuvant chemotherapy (three courses of 60 mg/m 2 doxorubicin plus 10 g/m 2 ifosfamide) with excellent partial response and underwent wide resection with radial nerve sacrifice (Fig

Thus, the findings must be replicated in a properly designed placebo controlled clinical trials

Fits the context

Missing doses or varying the time by several hours each day creates peaks and valleys in blood concentration that reduce overall effectiveness and can worsen side effects like nausea

Oral contraceptives are most effective at preventing pregnancy when taken every day