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LCINS development probably involves interactions between genetic risk, mediated by common and rare germline variants, and environmental exposures, including air pollution and particulate matter, with potential opportunities for broader lung cancer screening

The choice between them depends on goals, health status, and how aggressive intervention is desired

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Diabetologia 60 , 18511861 (2017)

mTOR inhibitors attenuate the HIF-1 pathway to suppress hypoxia-induced inflammation and affect the differentiation of immature DCs [99]

This antioxidant effect also enhances the activity of direct-acting antivirals such as telaprevir, especially in telaprevir-resistant replicon cells (Ezzikouri et al., 2015)