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An ideal PD model would exhibit a high level of construct validity, indicating a similar disease pathogenesis (e.g., involving oxidative stress, inflammation, complex I inhibition, or proteasome inhibition), face validity, reflecting comparable symptoms (e.g., dyskinesia, rigidity), biochemistry (e.g., decreased striatal DA and altered downstream neurochemistry), and pathology (nigrostriatal tract degeneration and Lewy body formation) to the human condition, as well as predictive validity, signifying the capacity to accurately identify clinically effective treatments (Betarbet et al
Medical assessment with blood tests is essential before self-supplementing if B12 deficiency is suspected
"Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing." Cell and Tissue Research, 2019;377(2):153-159
