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AD mostly affects those over 65 years of age, however, people in their late forties can develop the prodromal stage of AD- mild cognitive impairment (MCI)

This study analyses the complicated link between intestinal I/R damage and bloodbrain barrier (BBB) compromise, highlighting essential processes such as systemic inflammation, gut microbiota dysbiosis, oxidative stress, vagus nerve activation, and altered gut microbial metabolite production

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Together they address both existing spots and uneven tone

Fiber (particularly soluble fiber like psyllium) has its own evidence base for constipation management and is often used alongside probiotics

The article says providers often monitor imaging or DXA scans alongside inflammatory and metabolic markers to follow visceral-specific change