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The mechanism centers on its role in upregulating growth factors and modulating inflammation at injury sites without systemic immunosuppression

Newer compounds like retatrutide add a third receptor target (GIP, GLP-1, and glucagon) and may create unique nutritional challenges that have not yet been well-studied

BMJ open, 2020

While orlistat generally has a favorable safety profile, gastrointestinal side effects such as oily stools and flatulence are common and can impact treatment adherence

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rch.org.au/d_device_management/ Eli Lilly and Company (2024)