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Treatment with exenatide or liraglutide also decreased the expression of adipogenic and inflammatory markers in the adipose tissue of obese individuals with T2DM [53]
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Though exact dosing for retatrutide in the weight-loss setting is still being defined (because many of the uses remain investigational), in the key trial adults with obesity treated weekly showed large body weight reductions: e.g., up to ~17.5% at 24 weeks and up to ~24% at 48 weeks in certain dose groups
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