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187 , 188 The similar results of in vivo studies by Moogooee et al 189 showed that the amoxicillin-loaded hydrogels enhance drug concentration at the topical site than powder amoxicillin, meaning that therapeutic concentration can be achieved at a much lower dose which may reduce the adverse effects of amoxicillin in high doses

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[DOI] [PMC free article] [PubMed] [Google Scholar] 218

People with fibromyalgia seem to have higher levels of specific chemicals that send pain signals to the brain, as the result of the changes in the spinal cord and brain

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