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[8] SURPASS-2 : Tirzepatide (5, 10, 15 mg) reduced HbA1c by 2.01%2.30%, compared to 1.86% with semaglutide (1 mg)

Bloody stools, severe stomach pain, high fever, fainting, or inability to keep fluids down should not be ignored

[11] SELECT : SELECT was a large randomized, controlled trial that enrolled over 17,000 adults with established cardiovascular disease, an elevated BMI, but no diabetes

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Temporarily reduce high-fat foods, spicy dishes, high-fiber vegetables, and sugar alcohols, which can worsen loose stools during the adaptation phase