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If blood pressure rises above 140/90 or joint pain limits range of motion, discontinue IGF-1 LR3 for 57 days to allow fluid clearance before resuming at lower dose

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Okumura, C

Yet another article suggests 7-10 days refrigerated for some formulations

Roles of oxidant, activator, and surfactant on enhanced electrokinetic remediation of PAHs historically contaminated soil

This is followed by further phosphorylation of two additional docking tyrosine residues in the carboxy terminal tail (Tyr1349 and Tyr1356) which on activation can act as degenerate motif to recruit several other subsequent signaling molecules