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These include prolonged immobility, recent surgery, active cancer, pregnancy, use of combined hormonal contraceptives or hormone replacement therapy, previous history of blood clots, inherited thrombophilias, obesity, smoking, and increasing age

Heymsfield SB, Coleman LA, Miller R, et al

Medical weight loss should not be sold as effortless

Several large studies using electronic health records and insurance claims data have tracked people using GLP-1 medications for five years or more

This keeps side effects to a minimum, and it is not unusual for patients to experience some of the effects of tirzepatide, such as appetite reduction, in the early stages

GLP1-RA reduced the risk of the broad composite kidney outcome significantly by 17% which was only driven by a reduction in macroalbuminuria (26% reduction)