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The retrospective cohort study by Orandi et al., recently published in The Lancet Diabetes & Endocrinology , offers compelling evidence on the effectiveness and safety of glucagon-like peptide-1 (GLP-1) receptor agonists in kidney transplant recipients with pre-existing type 2 diabetes (1)
Becker Jr DW, Miller CJ, Keller HB
One of eight B complex vitamins, B12 plays a key role in red blood cell formation, cellular metabolism, nerve function, and DNA production
The increased level of insulin increases IGF-1 production by stimulating GH signaling ( 2 ( IGF-1 has been associated with the development and progression of some cancer types due to its function in activating the MAPK and PI3K signaling pathways ( in vivo study, the presence of high IGF-1 levels in the primary tumor environment tended to induce cancer cells to metastasize to bone, and cancer cell lines that highly expressed IGF1R were prone to display enlarged bone mass (50, 51)