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Vendor protocol specifies drawing 3 mL into the syringe from the BAC water vial, with the needle inverted and plunger withdrawn to the 3 mL mark, tapping to remove air bubbles

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These mechanisms can be classified under two main functional categories: (a) upregulation of the sense gene through direct interactions with the sense gene mRNA transcript, and (b) upregulation of the sense gene through ASO-mediated inhibition of the NAT

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If this occurs, slight dose adjustment (increasing by 50mcg if not already at 500mcg) may help