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2021 Nov:15

Brain support*

After 12 months of treatment, a significant improvement in FG, FI, HOMA-, and ISI were found in patients who were administered high-dose CAB whereas no significant change was found in those undergone pituitary surgery despite a greater degree of PRL reduction after the latter treatment, thus suggesting that the gluco-insulinemic metabolic improvement is mainly ascribable to CAB direct effect rather than the entity of PRL variation

Rationing system denies patients next-gen drugs To view or add a comment, sign in Narrow / Low Therapeutic Index Drugs (NTI Drugs) Some medications require very close monitoring because even a small difference in dose or blood concentration can lead to toxicity or treatment failure

P Natl Acad Sci USA 93:37043709 [DOI] [PMC free article] [PubMed] [Google Scholar] Li K, Reichmann H (2016) Role of iron in neurodegenerative diseases

Their ferroptosis inhibition is mediated by regular antioxidant pathways (ROS scavenging and iron chelation), rather than the redox-based catalytic recycling pathway by FER-1 514