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Mechanistic comparison: TB-500 primarily functions through actin binding and modulation of cell motility, with additional effects on PI3K/Akt/eNOS signaling, anti-inflammatory pathways, and antifibrotic activity

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Common sites include [11] : Abdomen (at least 2 inches away from navel) Outer thigh (middle third, avoiding inner thigh) Upper outer arm (triceps region, if sufficient subcutaneous tissue) Site rotation: Keep a rotation log to avoid using the same site within 12 weeks

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